We’re going all in on Biohub for the next chapter of our philanthropy.
We started with the goal to help scientists cure or prevent all diseases this century. With the progress in AI, we now think this will be possible much sooner. So we’re excited to push the frontiers of biology and AI to help make this happen.
AI + single-cell biology just opened a new door for treating diffuse midline glioma, one of the rarest childhood brain tumors.
Our team used AI to identify 3 existing drugs that work together to target all 7 of the cancer’s distinct cell states—confirmed at ~90% accuracy in the lab. A powerful example of how AI, biology and medicine can come together to unlock new treatment strategies, even for the rarest diseases.
Our co-founder @priscillachan penned a piece in @time about the newly announced Virtual Biology Initiative. By bringing together the global scientific community, we’re building an open data foundation to realize the promise of AI models for biomedical science 🧬
Learn more at the link in our stories.
#science #AI #biology
Today, we’re announcing the Virtual Biology Initiative —a new commitment to build the data foundation biology needs to power the next generation of AI models. This is the culmination of more than a decade of building open infrastructure for the scientific community.
The more we understand what happens inside cells, the closer we get to being able to cure or prevent disease. That’s what the Virtual Biology Initiative is ultimately about.
#OpenScience #AI #Biology
"We're fully committed to building tools that make every other scientist faster, more effective and more efficient at their work and research."
On the Future of Medicine Podcast, Priscilla Chan, pediatrician and co-founder of Biohub (@biohub ), shares how AI and cutting-edge scientific tools are transforming medicine.
From accelerating discovery to rethinking how we learn and practice care, this conversation explores what it will take to move medicine forward.
Check out the full episode: link in bio!
#FutureOfMedicine #AIinHealthcare #HealthInnovation
👀 the cover of Science Translational Medicine 🎉 Congrats to our Chicago Group Leader Daniel Zongjie Wang and team.
By adding three common amino acids alongside the delivery technology used in mRNA vaccines, they boosted how much medicine reaches cells—increasing delivery up to 20x and dramatically improving gene editing in preclinical models.
The impact: building toward more effective treatments for inflammatory diseases.
Read more at our link in bio.
This is what happens when our frontier AI and frontier biology combine: faster discovery, smarter science, and real results for patients.
7.5 million people in the U.S. live with psoriasis. Many still struggle — despite existing treatments.
Our team combined AI analysis with CRISPR experiments to identify overlooked biological pathways, then tested an existing asthma drug as a potential treatment.
And it worked.
🔗 Link in bio to read more.
The human body is an information system—and AI is helping us decode it to cure or prevent disease.
Learn how our scientists and researchers are using AI to simulate human cells, visualize hidden biology, and detect disease earlier at the link in bio.
What if we could keep a timeline of gene activity inside cells?
Many important biological processes, such as learning in brain cells or changes in cancer cells, depend on how gene activity evolves over time, not just at a single moment. Most tools that capture that information either require constant live imaging, which is hard to maintain, or they destroy the cell and lose important information.
This colorful image shows CytoTape inside a cell. Cytotape keeps a physical record of gene activity over time and works by building a long, flexible protein where different parts of the strand can mark when and how strongly certain genes were active.
Out in Nature today, this foundational work moves us closer toward better understanding learning, memory, and aging. 👏 Congrats to the team, including Biohub grantees Changyang Linghu and Denise Cai.
#imaging #science #biology #neuroscience
Using WaveOrder is like restoring an old photo but grounded in science, not aesthetics.
Even the best microscopes can leave scientists with distorted data. This bioimaging tool allows us to visualize what’s really happening inside cells and tissues. Each panel in this series shows close-up images before and after reconstruction by WaveOrder, a new tool from Biohub scientists. In the last panel, you can see cells captured by three different microscopy techniques (orientation, brightfield and fluorescence); the tiny green specks are immune cells known as macrophages, which are much sharper and easier to discern with WaveOrder.
By making the invisible visible, WaveOrder can strengthen cutting-edge imaging tools, helping to make AI models built on that data more accurate and reliable.
🔬 #microscopy #ScienceTools #BioImaging
Showcasing the future of AI-powered biology at #NeurIPS2025. From demos of our latest models to our virtual cells platform, we’re pushing the boundaries of frontier AI and frontier biology.
