38TERA

This is what gut support should look like. Thoughtfully formulated. Clinically informed. Designed to work with your body — not against it. DMN™ delivers targeted prebiotic nutrition that supports your gut at its foundation, helping nourish beneficial microbes and promote daily balance. No shortcuts. No unnecessary fillers. Just a smarter, more considered approach to gut health that fits seamlessly into your routine. Because real support doesn’t overwhelm your system — it strengthens it from within.

What you feel mentally doesn’t stay in your head. It shows up in your body. Research continues to show that gut health and mental health are biologically connected — not just through feelings, but through shared pathways that influence how your system responds day to day. Your gut microbiome plays a role in: → how your body processes stress → how your nervous system signals → how steady or reactive your system feels Which is why mental load doesn’t just feel emotional; it often shows up physically. Over time, this loop goes both ways. Your mental state can influence your gut environment, and your gut environment can influence how your system responds. So supporting your gut isn’t just about digestion, it’s about giving your body a more stable baseline to work from. That’s where daily microbiome support comes in. DMN is designed to do that through a combination of: - 3 types of prebiotic fibers - resistant starch - polyphenol-rich plant compounds These help feed beneficial bacteria, support diversity, and enable the production of compounds your body relies on for regulation. Because when your gut environment is more stable, Your system has a better foundation to handle what you’re carrying. Reference* ¹Jiang HY et al. Polygenic overlap and shared genetic architecture between gastrointestinal disorders and psychiatric disorders in 450,000 individuals. Nature Communications, 2023.

Our creator community is growing! We’re looking for intentional creators who are excited about setting a new standard for gut health. If you’re passionate about sharing your health journey, ingredient transparency, and science-backed gut health that fits into your real life, we want to hear from you. Hit the link in bio to apply to become a 38TERA Affiliate.

Stress doesn’t just pass through the body. It changes the conditions your gut microbes live in. When stress signals stay elevated, digestion patterns shift, gut motility changes, and the microbial balance can become less stable. Which is why supporting gut health isn’t just about removing symptoms. It’s about improving the daily inputs that shape the system. Things like dietary fiber, consistent routines, and the nutrients that feed beneficial microbes all influence how that ecosystem functions. Daily Microbiome Nutrition (DMN™) was designed to support that process — helping nourish the microbes that contribute to a balanced gut environment over time. Because real gut progress rarely comes from a single moment. It comes from consistent signals the microbiome can respond to. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The 15-day microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition and inflammation.

The 2026 ISAPP consensus made it official: Mediterranean and plant-based diets are THE dietary signature behind a healthy microbiome — because they’re rich in BOTH polyphenols and fiber, not just one of the two. If you read Plant Powered Plus, you’re already all over this. I knew it was true because I was reading the same papers the ISAPP authors were reading. But here’s something most people miss: your colon has different segments, and they are not fed the same way. -Fast-fermenting soluble fibers like inulin and FOS get consumed in the first half. -Resistant starch ferments slowly enough to reach the second half, delivering butyrate to the colonocytes — and epidemiology links higher RS intake to lower colorectal cancer risk. -Polyphenols feed populations like Akkermansia along the way and produce anti-inflammatory metabolites. Three prebiotic classes. Both halves of the colon. Most supplements miss this — they overemphasize fiber and ignore resistant starch and polyphenols. 38TERA DMN was built to deliver all three. The proof: at Day 11 of our 15-day M-SHIME® study — acetate +24%, propionate +25%, butyrate +22% — and DMN doses never changed. The microbes were adapting, getting better at the job over time. Feed your gut consistently and it grows stronger. Comment PREBIOTIC for the full ISAPP guidelines + a link to 38TERA. Follow @theguthealthmd for gut science you can actually use. And @38tera — the supplement company I co-founded, designed to my standards. Featured Study: ISAPP 2026 consensus statement on gut health. Nature Reviews Gastroenterology & Hepatology, Volume 23, May 2026.

Mood and stress don’t just live in your head. They start in your gut. Your microbiome is in constant conversation with your nervous system — through a signaling network called the gut–brain axis. It shapes how the body responds to stress signals and helps regulate communication between the digestive system and the brain. But those microbes can’t show up for you if you don’t show up for them. They run on specific fibers — ones they ferment into compounds that help support this signaling system. Cut off the fuel, and the conversation weakens. Daily Microbiome Nutrition (DMN™) gives them three types of prebiotics, each one chosen to feed the microbes that contribute to this connection. Because your microbiome doesn’t just digest what you eat. It helps shape the signals your brain receives. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The 15-day microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition and inflammation.

Most people associate serotonin with mood and the brain. But a large portion of it is actually produced in the digestive system¹. In the gut, serotonin helps control how food moves through the digestive tract by regulating the muscle contractions that push digestion forward. It also acts as a signal between the gut and the nervous system². So when people talk about the gut influencing mood or stress, part of that conversation comes back to the signaling pathways through the gut-brain axis³. Serotonin isn’t just involved in how we feel. It’s also part of the ongoing communication between the gut and the brain. Reference: ¹ Yano JM et al., Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 2015. doi:10.1016/j.cell.2015.02.047 ² Gershon MD, 5-Hydroxytryptamine (serotonin) in the gastrointestinal tract. Current Opinion in Endocrinology, Diabetes and Obesity, 2013. doi:10.1097/MED.0b013e32835bc703 ³ Carabotti M et al., The gut–brain axis: interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology, 2015. doi:10.20524/aog.2015.0014

This Green Berry Smoothie blends Daily Microbiome Nutrition (DMN™) into a bright, fruit-forward drink that nourishes beneficial microbes with three types of prebiotics. Simple to make. Refreshing to sip. And quietly supportive of the ecosystem inside your gut. 🍓

Digestive discomfort often leads people to focus on what to remove from their diet. But the microbiome responds to something simpler: what you feed it consistently. Daily Microbiome Nutrition (DMN™) makes that easy. 🫐 Mix it into a drink when you want something sweet & refreshing, or add it to meals and snacks throughout the day. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The 15-day microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition and inflammation.

Same routine. Every morning. Wherever you are. In 38TERA's 15-day M-SHIME® study, DMN™ produced a progressive rise in all three major short-chain fatty acids.* The microbiome wasn't just reacting to the prebiotic input. It was adapting to it. Tear. Pour. Go. *15-day in vitro microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition and inflammation.

The immune system doesn’t operate in isolation. A large portion of immune activity takes place in the gut, where immune cells constantly interact with the trillions of microbes living in the intestinal microbiome¹. Research shows these microbes help train immune responses, influence inflammation pathways, and support the body’s ability to recognize potential threats². The gut lining itself acts as a critical barrier, working alongside beneficial microbes to help maintain immune balance. But microbes rely on one key resource: fermentable fibers. When gut bacteria break down these fibers, they produce metabolites that help support the gut environment and the immune functions connected to it³. This is where Daily Microbial Nutrition becomes important DMN™ was designed to provide three types of prebiotic fibers microbes use to produce these beneficial compounds — helping support the ecosystem your immune system works alongside every day. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The 15-day microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition, and inflammation. References: ¹ Belkaid Y, Hand TW., Role of the microbiota in immunity and inflammation. Cell, 2014. doi:10.1016/j.cell.2014.03.011 ² Thaiss CA et al., The microbiome and innate immunity. Nature, 2016. doi:10.1038/nature18847 ³ Koh A et al., From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell, 2016. doi:10.1016/j.cell.2016.05.041

Most conversations about gut health start with food. But the microbiome responds to more than what’s on your plate. Daily movement, sleep patterns, stress levels, sunlight exposure, and regular routines all influence the environment your gut microbes live in¹². Your microbiome is constantly responding to the conditions you create for it — which is why consistency matters when it comes to microbial nutrition. Daily Microbiome Nutrition (DMN™) fits into that rhythm, making it easier to support the microbiome as part of the everyday patterns your gut responds to. Over time, those daily signals shape how the gut ecosystem functions. Which is why gut health is influenced by more than diet alone. Disclaimer:These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.The 15-day microbiome research study was conducted using the M-SHIME® (Simulator of the Human Intestinal Microbial Ecosystem), an advanced laboratory model that simulates the human gut environment using microbiomes derived from humans. This study was independently carried out by ProDigest (Belgium, 2025) to investigate the effects of DMN™ on gut-microbial activity, composition and inflammation. Reference: ¹ Zmora N, Suez J, Elinav E., You are what you eat: diet, health and the gut microbiota. Nature Reviews Gastroenterology & Hepatology, 2019. doi:10.1038/s41575-018-0061-2 ² Karl JP et al., Effects of psychological, environmental and lifestyle stressors on the gut microbiota. Current Opinion in Behavioral Sciences, 2018. doi:10.1016/j.cobeha.2018.04.003